Research advances in the domain of neuropeptide Y, stress, and depression may also have clinical implications for chronic-pain
sufferers, Mickey pointed out. In addition to finding that subjects who made little neuropeptide Y were the most emotionally
susceptible to physical pain, Mickey knows of one report that showed increases of blood neuropeptide Y associated with improvement
in chronic pain. "Perhaps individuals who produce more neuropeptide Y have stronger adaptive responses to pain, which results
in better long-term outcomes," he speculated.