Many psychiatric inpatients at risk for suicide improve rapidly shortly after admission. Improvement often means that the patient is no longer at acute high risk but has returned to chronic high risk for suicide at discharge, requiring comprehensive discharge planning. Most patients at moderate risk for suicide are treated as outpatients. The structured milieu, the initiation of treatment, the safety measures provided, and the peer interactions can promote rapid improvement. Antianxiety, antipsychotic, and sleep medications can be effective within minutes or hours. A good night’s sleep can result in rapid improvement in the patient’s clinical condition. Apart from medications, psychosocial interventions, especially group therapy, decrease anxiety, reduce isolation, improve reality testing, and provide needed support that shortens the hospital length of stay.