I must admit that I envy the resident class of 2001 as they begin their careers. In the last decade we have seen biopsychosocial research make broad gains in our field. Because of this new research and our broad psychotherapeutic traditions, each new resident has knowledge of human behavior and a treatment armamentarium that I could only dream of just a few decades ago. It will be up to us and the Class of 2001 to maintain the core principles of the doctor-patient relationship, privacy, and psychotherapy while incorporating these scientific advances into the daily clinical treatment of our patients. Each generation of psychiatrists has had the opportunity to define its roles in medicine and society and to make an impact on the burden of mental illness for individual patients’ and the public’s health. Now it is the Class of 2001’s turn.