Anbinder recounts the history of Five Points from its origins in the late 1700s as a site of slaughterhouses, meat-packing factories, and tanneries—industries whose noxious fumes and reliance on cheap, unskilled labor set the stage for an inexorable decline. As immigration swelled the city in the 1820s and 1830s, the small buildings that had dotted the neighborhood gave way to apartments and tenements, rented to African Americans and waves of poor immigrants—from Ireland, especially, but also from Italy, Germany, and Eastern Europe.