"This [was a] carefully done, long-term, prospective, cohort study," Deborah Cowley, M.D., a professor of psychiatry at the
University of Washington, commented in the March 21 Journal Watch Psychiatry. "Clinicians should view the menopausal transition and early postmenopause as a high-risk time for major depressive episodes
and consider antidepressants and/or psychotherapy, which remain the mainstay of treatment, given conflicting data about the
benefit of hormonal inventions."