"The article is part of a series of studies looking at the relationship between a specific variant of the COMT gene and antisocial behavior in children with ADHD," David Fassler, M.D., a clinical professor of psychiatry at the University of Vermont and a child and adolescent psychiatrist, explained to Psychiatric News. "The findings are consistent with previous reports regarding the existence of such an association. However, the authors further identify impaired social cognition as a potential mediating factor. As a whole, the results underscore the complexity of this emerging field. I would agree with the authors' conclusion that additional studies are necessary to replicate their findings. From a clinical perspective, one would hope that such efforts would ultimately lead to earlier recognition and more individualized treatment for children with ADHD."