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Clinical and Research News
Antipsychotics and Dementia Patients: Key Study Findings
Psychiatric News
Volume 46 Number 13 page 20-20
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  • Alzheimer's patients taking antipsychotics showed steady, significant declines over time in most cognitive areas, including in scores on the Mini-Mental State Examination (MMSE) and the cognitive subscale of the Alzheimer's Disease Assessment Scale.

  • Cognitive function declined more in patients receiving antipsychotics than in those given placebo on multiple cognitive measures, including the MMSE, the cognitive subscale of the Brief Psychiatric Rating Scale, and a cognitive summary score summarizing change on 18 cognitive tests.

  • Physicians prescribing antipsychotic medications for Alzheimer's patients with aggression and delusions should consider discontinuing the drugs if patients do not respond. 20_2/inline-graphic-1.gif

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