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TADS Basics
Published Online:1 Jul 2005https://doi.org/10.1176/pn.40.13.00400002a
The following is a brief summary of NIMH's Treatment of Adolescents with Depression Study (TADS), for which 12-week outcome data were published in the August 18, 2004, Journal of the American Medical Association.
Study Design: Randomized, blinded, multicenter comparing the effectiveness of four treatments for adolescent depression:
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Initial Outcomes: Percentage of the 439 adolescent patients who showed significant improvement at 12 weeks with a Clinical Global Impressions–Improvement score of 1 or 2:
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